• Fan Yang, Zhengang Liu, Yuhang Zhu, Qingsan Zhu, and Boyin Zhang.
• Department of Orthopaedics, China-Japan Union Hospital of Jilin University, Changchun, China.
• Medicine (Baltimore). 2022 Dec 9; 101 (49): e32051e32051.

AbstractInterpretation of the morphology and characteristics of soft tissues, such as paravertebral muscles and fat, has always been a "relative blind spot" in the spine. The imaging features of the non-bony structures of the spine have been studied and reinterpreted, and changes in the non-bony structure are associated with spinal disease. Soft tissue parameters such as, the "paraspinal muscle cross-sectional area," "subcutaneous fat thickness," and the "paraspinal muscle fat infiltration rate" on computed tomography, magnetic resonance imaging and other imaging techniques are reproducible in the diagnosis, treatment and prognosis of spinal disorders and have the potential for clinical application. In addition, focus on the association between sarcopenia and spinal epidural lipomatosis with spinal disorders is increasing. Currently, there is no summary of studies on fat and muscle in the spinal region. Given this, within the context of recent research trends, this article provides a synthesis of research on adipose and muscle tissue in the spine, discusses advances in the study of the imaging manifestations of these structures in spinal disorders, and expands the perspectives.Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc.

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