• Saudi Med J · Jan 2023

    Observational Study

    Impact of diabetes mellitus and co-morbidities on mortality in patients with COVID-19: A single-center retrospective study.

    • Anees A Sindi, Wail A Tashkandi, Mohammed W Jastaniah, Mohammed A Bashanfar, Ahmed F Fakhri, Fahad S Alsallum, Hamdan B Alguydi, Alyaa Elhazmi, Talal A Al-Khatib, Maha M Alawi, and Ibrahim Abushoshah.
    • From the Department of Anesthesia and Critical Care (Sindi, Abushoshah), from the Department of Surgery (Tashkandi), from the Department of Otolaryngology-Head Neck Surgery (Al-Khatib), from the Unit of Infection Control & Environmental Health (Alawi), Department of Medical Microbiology & Parasitology (Alawi), Faculty of Medicine (Jastaniah, Bashanfar, Fakhri, Alguydi, Alsallum), King Abdulaziz University and King Abdulaziz University Hospital, Jeddah, Saudi Arabia, from the College of Medicine (Elhazmi), Alfaisal University, and from the Research Center (Elhazmi), Dr. Sulaiman Al-Habib Medical Group, Riyadh, Kingdom of Saudi Arabia.
    • Saudi Med J. 2023 Jan 1; 44 (1): 677367-73.

    ObjectivesTo describe the effect of diabetes mellitus (DM) on clinical outcomes of patients admitted with COVID-19 infection.MethodsWe carried out a single center, observational, retrospective study. We included adult patients with laboratory-confirmed diagnosis of COVID-19 admitted to a tertiary hospital in Jeddah, Saudi Arabia, from April 2020 to December 2020. Electronic medical records were reviewed for demographics, clinical status, hospital course, and outcome; and they were compared between the patients with or without DM.ResultsOut of 198 patients included in the study, 86 (43.4%) were diabetic and 112 (56.5%) were non-diabetic. Majority of the patients were males 139 (70.2%) with a mean age of 54.14±14.89 years. In-hospital mortality rate was higher in diabetic patients than in non-diabetic patients (40 vs. 32; p=0.011). The most common comorbidity was hypertension (n=95, 48%) followed by ischemic heart disease (n=35, 17.7%), chronic kidney disease (n=17, 9.6%), and bronchial asthma (n=10, 5.1%).ConclusionThe risk of SARS-CoV-2 infection is higher among diabetic patients; particularly, those with preexisting co-morbidities or geriatric patients. Diabetic patients are prone to a severe clinical course of COVID-19 and a significantly higher mortality rate.Copyright: © Saudi Medical Journal.

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