• J Paediatr Child Health · Feb 1998

    Adenosine in the management of supraventricular tachycardia in children.

    • M C Sherwood, K C Lau, and G F Sholler.
    • Adolph Basser Cardiac Institute, Royal Alexandra Hospital for Children, Westmead, New South Wales, Australia.
    • J Paediatr Child Health. 1998 Feb 1;34(1):53-6.

    ObjectiveTo assess the efficacy and safety of adenosine in the management of supraventricular tachycardia in children.MethodologyA review of 43 children with supraventricular tachycardia who received intravenous adenosine between June 1992 and July 1995.ResultsThirty-five patients had re-entrant supraventricular tachycardia and eight patients had atrial tachydysrhythmias. Reversion to sinus rhythm occurred in 75% of episodes in all patients treated for supraventricular tachycardia, and in 96% of episodes in patients with re-entrant supraventricular tachycardia. Early re-initiation of supraventricular tachycardia after reversion to sinus rhythm occurred in 25% of episodes. Sixteen percent of patients reverted with the recommended 0.05 mg/kg starting dose, and 35% reverted with a dose of 0.1 mg/kg. Four patients were given adenosine as a diagnostic procedure to elicit occult pre-excitation. The most common side effects were brief feelings of discomfort. No serious side effects occurred.ConclusionAdenosine is safe and effective in the management of supraventricular tachycardia in children. A commencing dose of 0.1 mg/kg is appropriate.

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