• Moon Shrestha, Sudip Chandra Subedi, Sangam Shah, Jeny Acharya, Milan Regmi, and Neha Mehta.
• Tribhuvan University Teaching Hospital, Maharajgunj, Kathmandu, Nepal.
• JNMA J Nepal Med Assoc. 2022 Dec 1; 60 (256): 105910621059-1062.

UnlabelledAutoimmune hepatitis is a rare form of chronic liver inflammation that begins as acute hepatitis and progresses to chronic liver disease. It presents with varied clinical features from acute hepatitis to chronic liver diseases like chronic viral hepatitis and alcoholic liver disease, making it difficult to diagnose in the absence of a high index of suspicion and adequate laboratory support. Autoimmune hepatitis is divided into two categories autoimmune hepatitis-1 and autoimmune hepatitis-2 based on the antibodies involved. We discuss the case of a 37-year-old woman who developed autoimmune hepatitis-1, with swelling and epigastric pain. These symptoms later progressed to liver cirrhosis leading to the death of the patient. Autoimmune hepatitis is extremely sensitive to immunosuppressive medication, it is necessary to maintain a high suspicion index for the disease because a prompt diagnosis can be an integral step toward a better prognosis of the disease.Keywordsautoimmune hepatitis; case reports; chronic hepatitis; liver cirrhosis.

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