• Cleve Clin J Med · Mar 2023

    Review

    Smallpox and monkeypox: Looking back and looking ahead.

    • Paolo Sossai, Domenico Staiti, Massimiliano Cannas, and Piero Grima.
    • Director, Department of Medicine, European Center of Disaster and Emergency Medicine, Cailungo, Republic of San Marino paolo.sossai@unicam.it.
    • Cleve Clin J Med. 2023 Mar 1; 90 (3): 141144141-144.

    AbstractThe monkeypox (mpox) epidemic was declared a global health emergency in July 2022. The mpox virus belongs to the same virus family as the smallpox, or variola virus, but the infection is a less lethal threat than smallpox. Nevertheless, its relationship to smallpox is a worldwide concern, as is the discontinuation of universal smallpox vaccinations since the 1980s. Newer therapies and vaccines are available for both infections, including 2 antiviral drugs that can be used under certain conditions. Two vaccines have been developed for mpox prevention, but clarity is needed on when and how to use them. Preventive public health measures and prioritization of resources for managing infectious disease are concerns.Copyright © 2023 The Cleveland Clinic Foundation. All Rights Reserved.

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