• Jung Kwan Eun, Min Ji Park, Mee-Seon Kim, Man Hoon Han, Yong-Jin Kim, Hee Sun Baek, and Min Hyun Cho.
• Department of Pediatrics, Kyungpook National University, School of Medicine, Daegu, Korea.
• J. Korean Med. Sci. 2023 Mar 27; 38 (12): e89e89.

AbstractAs the global coronavirus disease 2019 (COVID-19) pandemic continues to sweep across the globe, reports of kidney involvement in adult patients infected with COVID-19 have been documented, and recently, cases in the pediatric population have also been reported. This report highlights the case of an 11-year-old boy who developed acute kidney injury presenting as gross hematuria, proteinuria, and hypertension immediately after a COVID-19 infection. A renal biopsy allowed us to diagnose the patient with post-COVID-19 infection-associated de novo crescentic immune-mediated glomerulonephritis. Oral prednisolone and cyclophosphamide treatments were initiated after methylprednisolone pulse therapy administration. Currently, the patient is receiving medical treatment for five weeks, and his renal function is gradually recovering. Previous studies have suggested that, although quite rare, a variety of kidney complications can occur after COVID-19 infection or vaccination, and it is recommended to monitor renal function through evaluation. Herein, we report a pediatric case of post-COVID-19 infection-associated de novo crescentic immune-mediated glomerulonephritis consistent with rapidly progressive glomerulonephritis.© 2023 The Korean Academy of Medical Sciences.

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