• P Lavrard-Meyer, Q Gomes De Pinho, A Daumas, A Benyamine, M Ebbo, N Schleinitz, J R Harlé, P A Jarrot, G Kaplanski, J Berbis, and B Granel.
• Assistance Publique des hôpitaux de Marseille (APHM), hôpital Nord, service de médecine interne, Aix-Marseille Université (AMU), Marseille, France.
• Rev Med Interne. 2023 May 1; 44 (5): 212217212-217.

IntroductionInfections are associated with morbimortality of patients with giant cell arteritis (GCA). The aim of this work was twofold: the identification of factors predisposing to the risk of infection and the description of patients hospitalized with an infection occurring during the treatment period of CAG.MethodsA monocentric retrospective study was conducted in GCA patients, comparing patients hospitalized for infection with patients without infection. The analysis included 21/144 (14.6%) patients with 26 infections (cases) and 42 control matched on sex, age, and diagnosis of GCA.ResultsBoth groups were similar except for a higher frequency of seritis in cases (15% vs. 0%, p=0.03). Relapses of GCA were less common in cases (23.8% vs 50.0%, p=0.041). Hypogammaglobulinemia was present during infection. More than half of the infections (53.8%) occurred in the first year of follow-up with an average dose of 15mg/day of corticosteroids. Infections were mainly pulmonary (46.2%) and cutaneous (26.9%).ConclusionFactors associated with infectious risk were identified. This preliminary monocentric work will continue with a national multicentre study.Copyright © 2023 Société Nationale Française de Médecine Interne (SNFMI). Published by Elsevier Masson SAS. All rights reserved.

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