La Revue de médecine interne
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This French National Diagnostic and Care Protocol (NDPC) includes both pediatric and adult patients with non-infectious chronic uveitis (NICU) or non-infectious recurrent uveitis (NIRU). NICU is defined as uveitis that persists for at least 3 months or with frequent relapses occurring less than 3 months after cessation of treatment. NIRU is repeated episodes of uveitis separated by periods of inactivity of at least 3 months in the absence of treatment. ⋯ Because local or systemic corticosteroids are usually necessary, these treatments and the risks associated with their prolonged use are the subject of particular attention and specific recommendations. The same information is provided for systemic immunomodulatory treatments, immunosuppressive drugs, sometimes including anti-TNFα antibodies or other biotherapies. Certain particularly important recommendations for patient management are highlighted in summary tables.
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An isolated elevation of aspartate aminotransferase (AST) is a diagnostic issue. Macro-aspartate aminotransferase (macro-AST) corresponds to the formation of complexes between AST and immunoglobulins. ⋯ The objective of this work is to increase awareness of this benign disorder among clinicians and biologists, as well as to aid in prescribing only the required tests.
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Post-Obstructive Diuresis (POD) is a polyuria that occurs following the release of an obstruction from the urinary tract that prevents the flow of urine. POD requires prompt diagnosis to avoid complications. ⋯ Restoration of renal homeostasis requires correction of blood volume and electrolyte disturbances to prevent complications, which can be serious. In this article, we propose a synthesis of knowledge on the subject, as well as a management strategy.
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Multicenter Study
[Hospitalization for infection in patients treated for giant cell arteritis: A single-centre retrospective study].
Infections are associated with morbimortality of patients with giant cell arteritis (GCA). The aim of this work was twofold: the identification of factors predisposing to the risk of infection and the description of patients hospitalized with an infection occurring during the treatment period of CAG. ⋯ Factors associated with infectious risk were identified. This preliminary monocentric work will continue with a national multicentre study.
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Artificial intelligence (AI) using deep learning is revolutionizing several fields, including medicine, with a wide range of applications. Available since the end of 2022, ChatGPT is a conversational AI or "chatbot", using artificial intelligence to dialogue with its users in all fields. Through the example of hydroxychloroquine (HCQ), we discuss its use for patients, clinicians, or researchers, and discuss its performance and limitations, particularly in relation to algorithmic bias. If AI tools using deep learning do not dispense with the expertise and experience of a clinician (at least, for the moment), they have a potential to improve or simplify our daily practice.