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Pol. Arch. Med. Wewn. · Apr 2023
ReviewExtracellular vesicles in vascular pathophysiology: beyond their molecular content.
- Ewa Ł Stępień, Martyna Durak-Kozica, and Paweł Moskal.
- Marian Smoluchowski Institute of Physics, Jagiellonian University, Kraków, Poland; Total-Body Jagiellonian-PET Laboratory, Jagiellonian University, Kraków, Poland; Center for Theranostics, Jagiellonian University, Kraków, Poland. e.stepien@uj.edu.pl
- Pol. Arch. Med. Wewn. 2023 Apr 19; 133 (4).
AbstractExtracellular vesicles (EVs) are released by all cells, both in physiological and pathological conditions. Their molecular charge and composition emerge as possible biomarkers, but EVs may also be considered for other clinical applications. This review discusses the role of other features of EVs, such as their lipid components or composition of glycans that form the EV corona and regulate EV biodistribution and uptake by target cells. The importance of EV electric charge has been discussed as a new insight into EV fate and destination.
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