• Anuj Bhardwaj, Rudra Kumar Gupta, Ayfer Atav Ates, Dian Agustin Wahjuningrum, Burçin Arıcan, Taher AlOmari, Alexander Maniangat Luke, and Ajinkya M Pawar.
• Department of Conservative Dentistry and Endodontics, College of Dental Science and Hospital, Indore, India.
• Patient Prefer Adher. 2023 Jan 1; 17: 102510341025-1034.

PurposeThis prospective single-blind, parallel-group, randomized clinical trial was aimed to compare the effect of three different rotary instrumentation systems ProTaper Next (PTN), Self-Adjusting File (SAF) and XP-endo Shaper (XPS) on postoperative pain and analgesic intakes.Patients And MethodsA total of 159 molars diagnosed with symptomatic irreversible pulpitis were randomly divided into three study groups according to the instrumentation techniques: PTN (n = 54), SAF (n = 52), and XPS (n = 53). The preoperative pain scores were taken before the onset of treatment in the groups. After a single appointment for root canal treatment, the patients were asked to rate the level of their pain according to the Visual Analog Scale (VAS) of 100 mm at 6, 24, 48, and 72-hour post-treatment intervals. Ibuprofen was prescribed to be taken while experiencing pain; patients were requested to note the number of pills consumed at intervals after treatment.ResultsThe patients in SAF and XPS groups had lower mean VAS scores than the PTN group at 24-, 48-, and 72-hour intervals (p < 0.05). The most common analgesic intake was optimally seen in the PTN group at a 6-hour interval. All shaping procedures caused postoperative pain, whose intensity decreased with time.ConclusionThe SAF and XPS groups had a lesser intensity of pain as well as minimum analgesic intakes as compared to the PTN group. All instrumentation systems moderately caused pain, and the PTN group experienced the highest pain among others.© 2023 Bhardwaj et al.

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