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- Randol Kennedy, Hussein Awada, Naga Vura, Daniela Ciltea, and Michael Morocco.
- Department of Internal Medicine, Cleveland Clinic Akron General Hospital, Akron, OH kennedr@ccf.org.
- Cleve Clin J Med. 2023 May 1; 90 (5): 307317307-317.
AbstractImmune checkpoint inhibitors are used more and more to treat several types of cancer, significantly extending cancer-free survival. However, concerns are growing about their toxic effects, which are many and varied. Endocrinopathies are some of the most frequently reported adverse effects, and thyroid dysfunction is the most common of these. Here, we review the incidence and severity of each immune checkpoint inhibitor-related endocrinopathy, possible factors related to toxicity risk, and principles of management.Copyright © 2023 The Cleveland Clinic Foundation. All Rights Reserved.
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