• Faisal S Alhajori, Mohammed H Makkawi, Sultan Z Alasmari, Ahmad A Shaikh, and Mirza A Baig.
• From the Ministry of Health (Alhajori); from Maternity and Children's Hospital (Baig), Al-Madinah Al-Munawwara; and from the Department of Clinical Laboratory Sciences (Makkawi, Alasmari, Shaikh), Faculty of Applied Medical Sciences, King Khalid University, Abha, Kingdom of Saudi Arabia.
• Saudi Med J. 2023 May 1; 44 (5): 504508504-508.

ObjectivesTo provide an updated estimate to the prevalence of pediatric hematological malignancies (HMs) in the Al-Madinah Al-Munawwara, Saudi Arabia.MethodsThis is a retrospective study that was carried out between 2016 and 2022. The study population was comprised of 171 children under 16 who had been diagnosed with HMs. The data was compiled from King Salman Medical City's Maternity and Children's Hospital, Al-Madinah Al-Munawwarah, Saudi Arabia.ResultsAmong the 171 HM patients (64% males and 36% females), 13 subtypes were identified, with B-cell acute lymphoblastic leukemia having the highest incidence (70.3%). Acute myelomonocytic leukemia (8.7%), T-cell acute lymphoblastic leukemia (4.7%), and acute promyelocytic leukemia (3.5%) were the next most common types of HMs. Other rare cases were also found.ConclusionPrevalence rate can be utilized to monitor the progression of disease incidence. Here, HMs demonstrated a pattern of increasing incidence in males over a 7-year period, with a higher rate in early childhood. There were 13 types of HMs diagnosed, with B-acute lymphocytic leukemia having the highest incidence. Although juvenile cancer is rare, it is nonetheless a significant cause of mortality in children. A successful prognosis requires prompt and accurate diagnosis and treatment.Copyright: © Saudi Medical Journal.

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