• Sobhy M Yakout, Ahmed M Isa, Amel A El-Sayed, and Ibrahim M Aziz.
• From the Department of Biochemistry (Yakout), College of Science; from the Department of Obstetrics and Gynecology (Isa, El-Sayed), College of Medicine; from the Department of Botany and Microbiology (Aziz), College of Science, King Saud University, Riyadh, Kingdom of Saudi Arabia.
• Saudi Med J. 2023 May 1; 44 (5): 450455450-455.

ObjectivesTo investigate levels of pentabromodiphenyl ether (PBDEs) in breast milk samples from healthy mothers who had lived in Riyadh for the last 5 years.MethodsIn this cross sectional study, 75 samples were collected and were extracted, cleaned by solid-phase extraction (SPE) and PBDEs analysis was done using gas chromatography-mass spectrometry.ResultsTotal PBDEs (∑PBDEs) ranged from 0.2 to 3.6 ng/g lipid weight (lw). BDE-47, -153, -99, and -209 were the dominant congeners. The mothers in this study consumed more meat (69%), followed by the egg (50%), and milk (36%). The majority of donors consumed fish (44%) and egg (33%) 2 times per week. The majority of the participating mothers had completed higher education (68%). All PBDE congeners were detected in the human breast milk samples with high detection frequency (98%). The dominant congener was BDE 47, accounting more than 39% of all BDE congeners, followed by BDE-99 and BDEs 153 which accounted for18% and 12% of the total BDE congeners respectively.ConclusionHigher rates of meat and poultry consumption were positively associated with higher breast milk levels of ∑PBDEs. The significant levels of PBDEs that occur in the meat and poultry reared in Saudi Arabia need further investigation especially as Saudis among largest consumers of poultry meat.Copyright: © Saudi Medical Journal.

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