• J Coll Physicians Surg Pak · May 2023

    Association of Polycystic Ovarian Syndrome with Endometrial Carcinoma among Premenopausal Females.

    • Khansaw Iqbal, Zohra Khanum, and Asia Parveen.
    • Department of Obstetrics and Gynaecology Unit II, Sir Ganga Ram Hospital, Lahore, Pakistan.
    • J Coll Physicians Surg Pak. 2023 May 1; 33 (5): 531534531-534.

    ObjectiveTo determine the association of polycystic ovarian syndrome (PCOS) with endometrial carcinoma in premenopausal females.Study DesignCohort study. Place and Duration of the Study: Department of Obstetrics and Gynaecology, Unit II, Sir Ganga Ram Hospital, Lahore, Pakistan, from July 2020 to January 2021.MethodologyFemales aged between 20-45 years, presenting with irregular uterine bleeding were included. Females with PCOS were considered as the exposed group and females without PCOS were considered as the unexposed group. Dilation and curettage was performed, and histopathology reports were assessed.ResultsThere were total 70 patients (35 in each group). The mean age was 34.93±8.64 years in the exposed and 30.92±5.98 years in the unexposed group. Frequency percentage of endometrial carcinoma was 34.3% (n=24) in the exposed and 15.7% (n=11) in the unexposed group (OR=10.54).ConclusionPCOS was found to be one of the risk factors for endometrial carcinoma.Key WordsPolycystic ovarian syndrome (PCOS), Endometrial carcinoma, Premenopausal pre-menopause.

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