• Taner Demirci, Muhammed Kizilgul, Hasret Cengiz, Mahmut Apaydin, Erman Cakal, and Ceyhun Varim.
• Department of Endocrinology and Metabolism, Sakarya University, Faculty of Medicine, Sakarya, Turkiye.
• J Coll Physicians Surg Pak. 2023 Apr 1; 33 (4): 416420416-420.

ObjectiveTo investigate the effect of subclinical hyperthyroidism on voice quality using acoustic analysis.Study DesignCross-sectional comparative study. Place and Duration of the Study: Department of Endocrinology and Metabolism, Ankara Diskapi Yildirim Beyazit Research and Education Hospital, Ankara, Turkey, from January to June 2020.MethodologyA total of 115 participants, with 60 patients with subclinical hyperthyroidism and 55 healthy volunteers, were evaluated and compared. Healthy volunteers with similar age and gender distributions were also evaluated and compared. Acoustic variables including average fundamental frequency (F0), relative average perturbation (RAP), jitter, shimmer, noise-to-harmonic ratio (NHR), and voice turbulence index (VTI) were measured and recorded.ResultsIn the patient group, acoustic voice analysis results were obtained for F0 224.97%, jitter 0.85%, RAP 0.51%, shimmer 3.16%, NHR 0.12 dB, and VTI 0.047, respectively. In the control group, these respective values were 219.60%; 0.74%; 0.46%; 3.11%; 0.12 dB; and 0.045, respectively. There was no statistically significant difference between the groups (p>0.05).ConclusionSubclinical hyperthyroidism does not cause a significant change in voice quality.Key WordsAcoustic analysis, Subclinical hyperthyroidism, Voice, Frequency.

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