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- Jonathan J Taliercio and Ali Mehdi.
- Department of Kidney Medicine, Glickman Urological & Kidney Institute, Cleveland Clinic, Cleveland, OH; Associate Professor of Medicine, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH TALIERJ@ccf.org.
- Cleve Clin J Med. 2023 May 24; 90 (6 suppl 1): e5e8e5-e8.
AbstractImmunoglobulin A nephropathy (IgAN) is the most common glomerulonephritis in the world. The etiology is unknown but a dysregulated T-cell immune response to viral, bacterial, and food antigens activating mucosal plasma cells to produce polymeric IgA has been proposed. No serological test exists to diagnosis IgAN. A definitive diagnosis requires kidney biopsy which is not always necessary. Kidney failure occurs in 20% to 40% of patients within 10 to 20 years.Copyright © 2023 The Cleveland Clinic Foundation. All Rights Reserved.
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