Iron deficiency in sepsis patients based on reticulocyte

Arch Med Sci · Jan 2023

Iron deficiency in sepsis patients based on reticulocyte hemoglobin and hepcidin concentration: a prospective cohort study.

Iron tests are deranged in sepsis; therefore new biomarkers should be used for diagnosis of iron deficiency (ID)/ID anemia (IDA). ⋯ Approximately half of sepsis patients are iron-deficient. Number of Rets may be a predictor of ID/IDA when Ret-He is not available. Hepcidin is a poor IDA predictor.

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- Piotr F Czempik and Agnieszka Wiórek.
- Department of Anaesthesiology and Intensive Care, Faculty of Medical Sciences, Medical University of Silesia, Katowice, Poland.
- Arch Med Sci. 2023 Jan 1; 19 (3): 805809805-809.
IntroductionIron tests are deranged in sepsis; therefore new biomarkers should be used for diagnosis of iron deficiency (ID)/ID anemia (IDA).MethodsDiagnosis of ID/IDA was based on reticulocyte (Ret) hemoglobin (Hb) equivalent (Ret-He) and Hb concentration, with hepcidin (Hep) determined retrospectively.ResultsThe prevalence of ID and IDA was 7% and 47%, respectively. The AUROCs for Rets number and Hep in prediction of ID/IDA were 0.69 and 0.62, respectively.ConclusionsApproximately half of sepsis patients are iron-deficient. Number of Rets may be a predictor of ID/IDA when Ret-He is not available. Hepcidin is a poor IDA predictor.Copyright: © 2023 Termedia & Banach.

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Iron deficiency in sepsis patients based on reticulocyte hemoglobin and hepcidin concentration: a prospective cohort study.

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