• Zhang Meijuan, Penglong Yu, Jie Yuan, Tao Yu, and Dan Sun.
• Shaanxi Provincial Hospital of Traditional Chinese Medicine, Xi'an, Shaanxi, P.R. China.
• Medicine (Baltimore). 2023 May 19; 102 (20): e33812e33812.

RationaleGastric mucosal ulcer caused by drug overdose is very rare in clinical practice, and here is a case of gastric antral ulcer caused by drug overdose.Patient ConcernsA 35-year-old housewife from a mountainous region in China took 48 Ibuprofen Sustained-Release capsules (300 mg/capsule) orally at 1 time. Because of severe tingling in the upper abdomen accompanied by a sharp increase in blood pressure, she came to the doctor 48 hours later.DiagnosesGastric antral ulcer (multiple stage A1), duodenococcitis, chronic nonatrophic gastritis, Helicobacter pylori infection, moderate depression, and cognitive impairment.InterventionsAcid suppression, antihypertensive and a series of symptomatic treatments.OutcomesAll somatic symptoms disappeared after a follow-up visit 2 months later.LessonsThis case provides valuable information to the clinic, through the compilation of literature and case analysis, the author found that paying attention to mental health, to women in poor areas and to women from families of low education level are indispensable in medical diagnosis and treatment.Copyright © 2023 the Author(s). Published by Wolters Kluwer Health, Inc.

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