• Benjamin Krishna, Mark Wills, and Nyaradzai Sithole.
• Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID), Cambridge CB2 0AW, UK.
• Br. Med. Bull. 2023 Sep 12; 147 (1): 6196-19.

IntroductionLong COVID is a chronic condition that follows after acute COVID-19 and is characterized by a wide range of persistent, cyclic symptoms.Sources Of DataPubMed search for publications featuring 'Long COVID' or 'post-acute sequelae of COVID-19'.Areas Of AgreementLong COVID occurs frequently post-acute COVID-19, with a majority of people experiencing at least one symptom (such as cough, fatigue, myalgia, anosmia and dyspnoea) 4 weeks after infection.Areas Of ControversyThe specific symptoms and the minimum duration of symptoms required to be defined as Long COVID.Growing PointsThere is a consistent reduction in Long COVID incidence amongst vaccinated individuals, although the extent of this effect remains unclear.Areas Timely For Developing ResearchThere is an urgent need to understand the causes of Long COVID, especially extreme fatigue more than 6 months after infection. We must understand who is at risk and whether reinfections similarly risk Long COVID.© The Author(s) 2023. Published by Oxford University Press.

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