• Yule Wei, Nan Yi, Yezhen Mo, and Yunxiao Liang.
• Department of Gastroenterology, The People's Hospital of Guangxi Zhuang Autonomous Region, Guangxi Academy of Medical Sciences, Nanning, China.
• Medicine (Baltimore). 2023 Jul 28; 102 (30): e34526e34526.

RationaleSmall intestinal hemangioma is a rare condition and very difficult to diagnose preoperatively. It can occur in all segments of the small intestine, but jejunum is common. Its common symptoms are gastrointestinal bleeding and chronic anemia, while intussusception, intestinal obstruction and perforation are rare. In recent years, the popularization and application of capsule endoscopy, computed tomographic enterography and double-balloon enteroscopy play vital roles in the diagnosis and management of small bowel bleeding. We report a case of gastrointestinal hemorrhage caused by of the small intestine hemangioma.Patient ConcernsA 56-year-old male complaint of hematochezia for 1 day with dizziness, fatigue, and vomiting of gastric contents.DiagnosisBased on the clinical, laboratory, imaging tests, endoscopy, laparoscopic approach and pathological examination, the patient was diagnosed with small intestinal hemangioma.InterventionsSegmental resection was performed for the small intestinal hemangioma by a laparoscopic approach.OutcomesThe patient was discharged without operation complications, and his hemoglobin increased to 130 g/L at the second month after the operation.LessonsSmall intestinal hemangioma is a rare condition without specific symptoms and can cause gastrointestinal bleeding. The possibility of small intestinal hemangioma should be considered with unexplained gastrointestinal bleeding. Surgical resection is the preferred treatment option for symptomatic hemangiomas. Furthermore, double-balloon enteroscopy can increase the diagnostic yield. Applying endoscopic titanium clip combined with Indian ink marking can obtain an accurate positioning before surgery.Copyright © 2023 the Author(s). Published by Wolters Kluwer Health, Inc.

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