• Ufaq Rao and Mohsin Fazal.
• Department of Oral and Maxillofacial Surgery, Islamic International Dental College and Hospital, Islamabad, Pakistan.
• J Coll Physicians Surg Pak. 2023 Aug 1; 33 (8): 895899895-899.

ObjectiveTo compare ketorolac with Tramadol as a preemptive analgesic in impacted third molar surgery in terms of mean pain score, mean time of first analgesic and mean total analgesic consumption postoperatively.Study DesignExperimental study. Place and Duration of the Study: Department of Oral and Maxillofacial Surgery, Islamic International Dental Hospital, (IIDH) Riphah International University, Islamabad, from March 2018 to March 2020.MethodologyNinety-four patients, aged 18-45 years with impacted third molars were divided into two groups. Preoperatively oral tramadol 50 mg was given in group A and oral ketorolac 10 mg was given in group B. Pain score was measured 3 hours postoperatively, using the visual analogue scale (VAS), the time was noted for first analgesic consumption in hours and total consumption of analgesics.ResultsThe mean postoperative pain was measured for both groups. Pain was significantly less in Group B. The mean pain score was 4.02+1.20 in group A and 3.42+1.08 in group B measured at 3 hours postoperatively (p=0.02). The mean time interval for 1st postoperative analgesic was 2.90+1.24 hours in group A and 3.61+1.02 in group B (p=0.007). The mean total analgesic consumption was 3.75+1.27 grams in Group A and 2.27+1.74 grams min Group B (p=0.006).ConclusionPreemptive Ketorolac has a more prolonged analgesic effect as compared to tramadol.Key WordsPreemptive analgesia, Tramadol, Ketorolac, Pain score, Third molar surgery.

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