• Amela Dedeić Ljubović, Ðana Granov, Erna Husić, Džemilja Gačanović, Jasmina Halković, Azra Čamdžić Lab Ing, Šejla Kotorić Keser, and Svjetlana Loga Zec.
• From the Unit of Clinical Microbiology, Clinical Center of the University of Sarajevo, Sarajevo, Bosnia and Herzegovina.
• Saudi Med J. 2023 Aug 1; 44 (8): 801807801-807.

ObjectivesTo assess the prevalence of these resistant strains in the overall isolates of Klebsiella pneumoniae (K. pneumoniae) in hospital settings.MethodsThis retrospective study was conducted from November 2020 to November 2021. The identification and antibiotic susceptibility testing were performed using standard laboratory methods according to the EUCAST standards. The detection of ESBL and carbapenemase production was performed using phenotypic methods such as E-test, combined-disk test with various inhibitors (ROSCO Diagnostica A/S), chromogenic medium for the detection of ESBL/carbapenemase-producing Enterobacteriaceae (CPE) isolates, and the VITEK 2 Compact system (BioMerieux).Results944 isolates of K. pneumoniae were detected in various clinical specimens. Among these, ESBL-producing strains were detected in 349/944 (37%), whereas carbapenem- resistant strains in 188/944 (20%) of the isolates. The remaining isolates (407/944 [43%]) belonged to the wild type. ESBL isolates were the most common in wound swabs (138 [39.5%]), whereas CRKP isolates in screening samples (110 [58.5%]). The majority of ESBL isolates were detected in surgical departments (105 [30.1%]), whereas CRKP isolates in adult intensive care unit departments (79 [42.%]).ConclusionOur results show an increasing frequency of CRKP strains. This presents a significant issue in terms of infection prevention and control in hospital settings.Copyright: © Saudi Medical Journal.

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