• Marat Mirzabaev, Ermek Dusembekov, Gani Akhanov, Aida Zhailaubayeva, and Victor Karavayev.
• Department of Neurosurgery, Asfendiyarov Kazakh National Medical University, Almaty, Kazakhstan. Electronic address: marat.mirzabaev@aol.com.
• World Neurosurg. 2023 Dec 1; 180: e163e170e163-e170.

ObjectiveA topic of current research is the development of a new approach to the diagnosis and treatment of severe brain injury taking into consideration its main pathophysiological mechanism-idiopathic intracranial hypertension syndrome. The goal of this study was to identify Doppler patterns of unfavorable craniocerebral injury conditions to form a consistent algorithm of treatment measures to reduce secondary brain damage in patients with severe craniocerebral trauma.MethodsTranscranial Doppler imaging is a prospective method, which allows quick and noninvasive assessment of the intracerebral blood flow dynamics right at the patient's bedside. Due to the operator-dependent nature of this method, clinical interpretation can often be contradictory. As a result, no clear criteria for therapy correction have yet been formulated based on this neuroimaging method.ResultsAnalysis of the therapy performed allowed us to specify the options for the hyperosmolar solutions for the correction of idiopathic intracranial hypertension syndrome.ConclusionsNo statistically significant difference in effectiveness was shown between mannitol and hypertonic saline solutions.Copyright © 2023 Elsevier Inc. All rights reserved.

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