• J Clin Anesth · Aug 2008

    Randomized Controlled Trial Comparative Study

    Remifentanil-propofol versus fentanyl-propofol for monitored anesthesia care during hysteroscopy.

    • Jung-Hee Ryu, Jae-Hun Kim, Kum-Suk Park, and Sang-Hwan Do.
    • Department of Anesthesiology and Pain Medicine, Seoul National University College of Medicine, Seoul, South Korea.
    • J Clin Anesth. 2008 Aug 1;20(5):328-32.

    Study ObjectiveTo compare the efficacy of remifentanil-propofol with that of fentanyl-propofol for monitored anesthesia care during hysteroscopy.DesignProspective, randomized study.SettingOperating room and postanesthesia care unit of a university hospital.Patients30 ASA physical status I and II adult patients undergoing hysteroscopic procedures.InterventionsAfter propofol infusion, patients received a bolus of remifentanil (group R, 0.5 microg/kg) or fentanyl (group F, 1 microg/kg) 4 minutes before starting the procedure and then received a continuous infusion of remifentanil (group R, 0.05 microg/kg per min) or bolus doses of fentanyl (group F, 0.5 microg/kg).Measurements And Main ResultsPatients in group R had lower pain scores than patients in group F (0-0 vs 0-7, P < 0.05) and more stable blood pressures (74 +/- 15 vs 85 +/- 9 mmHg, P < 0.05) one minute after the start of the procedure. However, no differences were observed in other variables (recovery profiles and satisfaction scores).ConclusionRemifentanil seems to be a safe and effective analgesic adjunct for monitored anesthesia care of hysteroscopic surgery.

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