• Aimun Raees, Zahabia Sohail, and Om Parkash.
• Department of Medicine, The Aga Khan University Hospital, Karachi, Pakistan.
• J Coll Physicians Surg Pak. 2023 Jan 1; 33 (1): 424442-44.

AbstractSystemic Lupus Erythematosus (SLE) is a chronic inflammatory disorder with heterogeneous presentation and clinical course. We present a case of a young female with an atypical presentation of SLE. A young woman with no known prior comorbidities presented with a history of chronic diarrhoea, vomiting, and weight loss, followed by generalized weakness. An extensive workup was done and she was diagnosed with lupus enteritis based on history, laboratory investigations, and imaging findings. She was given pulse therapy to which she responded very well. The case describes the importance of high clinical suspicion and timely intervention as well as adds to the evidence on a rare clinical entity of lupus enteritis. Key Words: Systemic lupus erythematosus, Lupus enteritis, Autoimmune disorder, Chronic diarrhoea.

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