• J Coll Physicians Surg Pak · Jan 2023

    Case Reports

    Unusual Allergic Reaction to Intralesional Bleomycin in Periocular Haemangioma.

    • Saba Alkhairy and Nimra Akram.
    • Department of Ophthalmology and Visual Sciences, Civil Hospital Karachi, Dow University of Health Sciences, Karachi, Pakistan.
    • J Coll Physicians Surg Pak. 2023 Jan 1; 33 (1): 777977-79.

    AbstractCapillary haemangiomas are the most common periocular tumours among children. Most of them resolve spontaneously. The most common indication for intervention is visual impairment. Intralesional bleomycin injections have been used successfully to treat periocular haemangiomas resistant to conventional treatment modalities. In the literature, the most commonly reported side effects of intralesional bleomycin are local skin reactions like erythema, swelling, and pigmentation. Here, we report a highly unusual case of a severe allergic reaction to the fourth dose of intralesional bleomycin injection in a periocular haemangioma in a 7-year child. The clinical features and subsequent management of the patient are also discussed. Key Words: Anaphylaxis, Intralesional bleomycin, Periocular haemangioma.

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