• Pain Pract · Feb 2024

    Review

    An overview of local anesthetics in over-the-counter products.

    • Tyler A Kalajian, Joseph A Cannella, Ananya Vasudevan, Jack Mizelle, Luis F Rendon, Ala Nozari, and Rafael Ortega.
    • Boston University School of Medicine, Boston, Massachusetts, USA.
    • Pain Pract. 2024 Feb 1; 24 (2): 364373364-373.

    AbstractOver-the-counter (OTC) local anesthetics have historically been used to alleviate pain in several common conditions including toothache and sore throat. With a rise in chronic conditions and an aging population, there has been an increase in associated chronic pain-related disorders. Individuals with chronic pain often seek OTC treatments for quick and accessible pain relief. There are several common OTC local anesthetics, including benzocaine, lidocaine, and dibucaine, which are readily available to patients in several formulations. In order to appropriately advise patients on the use of local anesthetics, it is important to understand their key characteristics, including the mechanism of action, clinical properties, pharmacokinetics, clinical applications, and adverse reactions, which may occur.© 2023 World Institute of Pain.

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