• Lin Zhang, Cao-Qing Yin, Shi-Jie Sun, Xue-Qin Teng, Dong-Yan Li, Jie Sun, and Yuan-Yong Cui.
• School of Medicine and Nursing, Dezhou University, Dezhou, Shandong, China.
• Medicine (Baltimore). 2023 Oct 6; 102 (40): e35489e35489.

ObjectiveTo explore the effects of comprehensive nursing intervention on in vitro fertilization (IVF) and pregnancy outcomes in patients with polycystic ovary syndrome (PCOS).MethodA total of 130 patients with PCOS admitted to our hospital from April 2021 to March 2023 were selected as the research subjects. They were evenly divided according to a random number table method. The control group received routine care for the patients, while the study group received comprehensive care for the patients. The IVF, pregnancy outcomes, negative emotional changes, serum and follicular fluid (FF) amyloid-related protein and C-reactive protein (CRP) levels of the 2 groups of patients were compared.ResultThe data on IVF rate and pregnancy rate in the study group were significantly better than those in the control group (P < .05). The SAS and SDS scores of the study group patients after intervention were significantly lower than those of the control group (P < .05). After intervention, the levels of serum and FF amyloid associated protein and CRP in the study group were significantly lower than those in the control group (P < .05).ConclusionPatients with PCOS who receive comprehensive care can increase their probability of IVF, improve their pregnancy outcomes, and have a positive significance in reducing negative emotions.Copyright © 2023 the Author(s). Published by Wolters Kluwer Health, Inc.

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