• Bonnie D Snyder, Molly R Van Dyke, Robert G Walker, Andrew J Latimer, Bartholomew C Grabman, Charles Maynard, Thomas D Rea, Nicholas J Johnson, Michael R Sayre, and Catherine R Counts.
• University of Washington, School of Medicine, USA. Electronic address: snyderb9@ucmail.uc.edu.
• Resuscitation. 2023 Dec 1; 193: 109991109991.

IntroductionLittle is known about the impact of tidal volumes delivered by emergency medical services (EMS) to adult patients with out-of-hospital cardiac arrest (OHCA). A large urban EMS system changed from standard adult ventilation bags to small adult bags. We hypothesized that the incidence of return of spontaneous circulation (ROSC) at the end of EMS care would increase after this change.MethodsWe performed a retrospective analysis evaluating adults treated with advanced airway placement for nontraumatic OHCA between January 1, 2015 and December 31, 2021. We compared rates of ROSC, ventilation rate, and mean end tidal carbon dioxide (ETCO2) by minute before and after the smaller ventilation bag implementation using linear and logistic regression.ResultsOf the 1,994 patients included, 1,331 (67%) were treated with a small adult bag. ROSC at the end of EMS care was lower in the small bag cohort than the large bag cohort, 33% vs 40% (p = 0.003). After adjustment, small bag use was associated with lower odds of ROSC at the end of EMS care [OR 0.74, 95% CI 0.61 - 0.91]. Ventilation rates did not differ between cohorts. ETCO2 values were lower in the large bag cohort (33.2 ± 17.2 mmHg vs. 36.9 ± 19.2 mmHg, p < 0.01).ConclusionUse of a small adult bag during OHCA was associated with lower odds of ROSC at the end of EMS care. The effects on acid base status, hemodynamics, and delivered minute ventilation remain unclear and warrant additional study.Copyright © 2023 Elsevier B.V. All rights reserved.

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