• Tatjana Šimurina, Boris Mraović, Miroslav Župčić, Sandra Graf Župčić, and Marina Vulin.
• 1Department of Anesthesiology, Resustitation, Intensive Medicine and Pain Management, Faculty of Medicine, "Josip JurajStrossmayer" University, Osijek, Croatia; 2Department of Health Studies, University of Zadar, Zadar, Croatia; 3Department of Anesthesiology, Reanimatology and Intensive Care Medicine, Zadar General Hospital, Zadar, Croatia; 4Department of Anesthesiology and Perioperative Medicine, School of Medicine, University of Missouri, Columbia, USA; 5School of Medicine, University of Rijeka, Rijeka, Croatia; 6Clinic of Anesthesiology and Intensive Care Medicine, Clinical Hospital Centre Rijeka, Rijeka, Croatia; 7Clinic of Neurology, Clinical Hospital Centre Rijeka, Rijeka, Croatia.
• Acta Clin Croat. 2019 Jun 1; 58 (Suppl 1): 536153-61.

AbstractThe objective of this clinical update, based on recently published literature, was to discuss incidence and characteristics of the most relevant clinical adverse effects associated with local anesthetic and steroid use in regional anesthesia and treatment of acute or chronic pain. A comprehensive review of the English-language medical literature search utilizing PubMed, Ovid Medline® and Google Scholar from 2015 to 2018 was performed. This narrative review provides anesthesia practitioners with updated evidences on complications and contraindications of local anesthetic and steroid use with emphasis on current points of view regarding prevention, early diagnosis and treatment of adverse events.

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