• Fazal Ur Rehman, Syeda Tayyaba Rehan, Fatima Yousaf, Navin Rathore, Bakhtawar Jamal Rind, Mohammed Mahmmoud Fadelallah Eljack, Muhammad Sohaib Asghar, and Farruk Omair.
• Department of Medicine, Aga Khan University Hospital, Karachi, Pakistan.
• Medicine (Baltimore). 2023 Oct 27; 102 (43): e35719e35719.

RationaleDengue fever is a widespread mosquito-borne viral disease, most prevalent in the tropical and subtropical areas of the world. There has been a significant rise in the incidence and number of outbreaks of dengue in recent years, which has made it a matter of global concern. It may be associated with a number of renal complications, ranging from hematuria, proteinuria, glomerulonephritis, and acute tubular necrosis. However, renal cortical necrosis (RCN) is a rare renal complication of this disease.Patients ConcernsWe report the case of a young gentleman who presented with fever, vomiting, and anuria. On workup, he was found to be having complicated Dengue fever with RCN resulting in acute renal failure.DiagnosisTo the best of our knowledge, RCN is not a reported renal complication of dengue fever.Interventions And OutcomesOur report highlights the importance of early consideration of renal cortical necrosis in patients with dengue fever and persistent anuria.LessonThis would allow for better disease prognostication while enabling physicians to develop more effective treatment strategies.Copyright © 2023 the Author(s). Published by Wolters Kluwer Health, Inc.

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