• Ji Cheng, Jun-Yan Qu, Michael R Hamblin, Dan Hao, and Xiang Wen.
• Department of Dermatology, West China Hospital, Sichuan University, Chengdu, China.
• Medicine (Baltimore). 2023 Oct 27; 102 (43): e35781e35781.

RationaleAmong numerous types of nontuberculous mycobacterial infections, Mycobacterium avium complex is a related group of species, which can cause various diseases in humans. Mycobacterium marseillense is a member of the Mycobacterium avium complex, which accounts for only a small proportion of species, but causes rare diseases affecting the lungs, lymph nodes, skin, and tendon sheath. So far, very few cases have been reported.Patient ConcernsA 76-year-old male of peculiar skin infection. Metagenomic Next Generation Sequencing and bacterial culture of skin secretions revealed M marseillense. To the best of our knowledge, we report the first patient diagnosed with disseminated M marseillense infection. Here, we identified only 8 other reports of patients with M marseillense infection.DiagnosesDisseminated M marseillense infection.InterventionsThe patient was treated with clarithromycin, rifampicin, moxifloxacin, and ethambutol.OutcomesThe skin lesions of the patient showed significant improvement, and his pruritus and limb pain were notably reduced after 7 months of follow-up.LessonsMetagenomic Next Generation Sequencing may be a useful tool to diagnose M marseillense infection, but the results should be confirmed by culture and mycobacterial identification.Copyright © 2023 the Author(s). Published by Wolters Kluwer Health, Inc.

10 keywords...

hide…