• Yi-Hang Ding, Jing-Yi Chen, En-Shuang Zheng, Zi-Qing Wang, Ri-Sheng Liang, Song-Sheng Shi, and Xian-Kun Tu.
• , Department of Neurosurgery, Fujian Medical University Union Hospital, Fuzhou, China.
• Medicine (Baltimore). 2023 Oct 27; 102 (43): e35684e35684.

AbstractAt present, detailed demographic and clinical data of moyamoya disease (MMD) in the population of Southeast China are lacking. Therefore, this study aimed to evaluate the epidemiological and clinical features of MMD in Southeast China. Our cohort included 170 patients diagnosed with MMD over the preceding 5 years. Clinical characteristics were obtained through a retrospective chart review, while follow-up information and outcomes were obtained through clinical visits and imaging. The median age at symptom onset was 49 years (range 4-73), with a peak in the age distribution observed at 41 to 60 years. The female-to-male ratio was 1.125 (90/80), and the ratio of the ischemic type to the hemorrhagic type was 2.33 (119/50). The most common initial symptom was an ischemic event. The 5-year Kaplan-Meier risk of stroke was 4.9% for all patients treated with surgical revascularization. Of all patients, 83.9% were able to live independently with no significant disability, and 89.8% showed improved cerebral hemodynamics. Our study provided detailed demographic and clinical data on Southeastern Chinese patients with MMD, which was consistent with findings in other parts of China. Raising clinical awareness of MMD in primary hospitals is important to facilitate early diagnosis and timely treatment of MMD patients.Copyright © 2023 the Author(s). Published by Wolters Kluwer Health, Inc.

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