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- Stephen M Pastores.
- Program Director, Critical Care Medicine; Vice-Chair of Education, Department of Anesthesiology and Critical Care Medicine, Memorial Sloan Kettering Cancer Center; Professor of Medicine in Anesthesiology and Medicine, Weill Cornell Medical College, New York, NY; researcher and member of guidelines committees on the use of corticosteroids in acutely ill patients pastores@mskcc.org.
- Cleve Clin J Med. 2022 Sep 1; 89 (9): 505511505-511.
AbstractCritical illness-related corticosteroid insufficiency (CIRCI) is a state of systemic inflammation involving dysregulation of the hypothalamic-pituitary-adrenal axis, altered cortisol metabolism, and tissue resistance to corticosteroids. Many conditions may be associated with CIRCI, including sepsis, septic shock, acute respiratory distress syndrome, and severe community-acquired pneumonia. Recommendations and practice for diagnosing and treating this condition have evolved as information has emerged. Here, the author reviews the current thinking.Copyright © 2022 The Cleveland Clinic Foundation. All Rights Reserved.
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