• C Olutayo Alebiosu, Olugbenga O Ayodele, Adigun Abbas, and A Ina Olutoyin.
• Department of Medicine, Olabisi Onabanjo University Teaching Hospital, P O Box 4622, Dugbe Post Office, Ibadan, Oyo State, Nigeria. dralechristo@yahoo.com
• Afr Health Sci. 2006 Sep 1; 6 (3): 132138132-8.

UnlabelledBACKGROUND AND OBJECTIVES OF THE STUDY: Chronic kidney disease is a common cause of morbidity and mortality in Nigeria. This study aims at determining the pattern of chronic renal failure (CRF) in a Nigerian University Teaching Hospital.MethodsThe study was a 10-year retrospective study of consecutive cases of CRF seen at Olabisi Onabanjo University Teaching Hospital, Sagamu, Ogun State, Nigeria.ResultsThe frequency of CRF in the population was 3.6% (182 of 5,107). There were 90 males and 63 females (1.42:1). The peak age was between 20-49 years, with a mean of 39.6 +/- 14.8 (range 14-72 years). The commonest causes were chronic glomerulonephritis 63(41.2%), hypertensive nephrosclerosis 40(26.1%) and diabetes mellitus 20(13.1%). The commonest symptoms were oedema, vomiting, oliguria and dyspnea occurring at 118(77.1%), 96(62.7%), 89(58.2%) and 87(56.9%) respectively. The mean creatinine clearance value at presentation was 6.5 +/- 8.1 mls/min, while the commonest complications were hypertension 68 (44.4%), biventricular failure 32 (20.9%) and urinary tract infection 29 (19%). The mean presenting systolic and diastolic blood pressures were 167.34 +/- 37.6 mm Hg and 106.03 +/- 28.9 mmHg respectively. The mean total haemodialysis session per patient was 3.5 +/- 1.6 (range 1-7 sessions). Only 34(22.2%) of the patients were able to afford haemodialysis. The majority 21(61.8%) of these could only afford 3 haemodialysis sessions while only 2(5.9%) patients had up to 7 dialysis sessions in the center.ConclusionChronic glomerulonephritis, hypertensive nephrosclerosis and diabetes mellitus are the commonest causes of chronic renal failure in Nigeria. Most of the patients presented late. Cardiovascular complications and infections were responsible for a greater morbidity among the patients.

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