• Zhongxue Ye, Yafen Jiang, Kun Yan, and Chen Yu.
• Department of Gynecology, Ningbo No. 2 Hospital, Ningbo, China.
• Medicine (Baltimore). 2023 Nov 10; 102 (45): e35964e35964.

RationaleUterine torsion and giant leiomyoma are both rare diseases. Uterine torsion combined with giant leiomyoma with degeneration or infarction is easy to be misdiagnosed. We wrote this case to increase the accuracy and timeliness of medical staff's diagnosis and treatment of uterine fibroids combined with uterine torsion.Patient ConcernsWe present a case of uterine torsion with degeneration and infarction of giant leiomyoma in a 66-year-old postmenopausal woman, who had a lump in her pelvis 10 years ago and suffered from acute abdominal pain half a day before hospitalization.DiagnosisThe patient was considered as uterine torsion with huge abdominal mass by computed tomography and enhanced magnetic resonance imaging, and finally diagnosed as uterine torsion with giant leiomyoma through surgery and pathological examination.Interventions And OutcomesThe patient underwent exploratory laparotomy. In addition to the removal of huge uterine fibroids, the hysterectomy with double appendages was conducted. The histopathologic analysis showed "(Uterine tumor) leiomyoma with extensive edema, degeneration, infarction and calcification." The patient recovered well after operation and kept healthy in the follow-up to date.LessonsAlthough uterine torsion is extremely rare, early diagnosis and treatment are essential to prevent serious complications.Copyright © 2023 the Author(s). Published by Wolters Kluwer Health, Inc.

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