• Charlotte C Poot, Jasmijn de Boer, Lyè Goto, Susanne J van de Hei, Niels H Chavannes, Valentijn T Visch, and Eline Meijer.
• Department of Public Health and Primary Care, Leiden University Medical Centre, Leiden, The Netherlands.
• Patient Prefer Adher. 2023 Jan 1; 17: 271927362719-2736.

ObjectiveThis study aimed to design a persuasive game, using objective adherence data, to motivate people with asthma to adhere to their medication regimen.MethodsA participatory user-centered design approach was employed, involving end-users and other stakeholders throughout the study. The approach consisted of four phases. Semi-structured interviews and a survey were conducted to understand user needs and reasons for poor adherence (Phase 1: define). Key themes were identified, leading to the formulation of behavior change strategies and design and game requirements. Several design directions were ideated, resulting in a concept for a serious game (Phase 2: ideate). Two rounds of user-tests were performed to evaluate a prototype of the serious game in terms of usability, perceived impact on medication adherence and motivation (Phase 3: prototype and Phase 4: evaluate).ResultsFindings from semi-structured interviews (n = 6) and the online survey (n = 20) revealed that people's non-adherence was often attributed to the perception of asthma as an episodic condition, the delayed experienced effect of maintenance inhalers, and lack of knowledge regarding difference of effect between maintenance and reliever inhalers. The study used behavior change strategies to translate these insights into design requirements for the development of the narrative-based persuasive game Ademgenoot. This six-week challenge-based game combines various behavior change strategies, including personal goal setting and continuous visual feedback, as well as persuasive game design elements, such as a narrative and rewards, with the aim of enhancing motivation to adhere to their medication regimen. User-testing (n = 8; round 1 and 2) showed that Ademgenoot is feasible in clinical practice and has the potential to support people with mild asthma in adherence to their maintenance medication.DiscussionFuture efforts should be directed towards a larger evaluation to assess the impact on motivation and inhaler use behaviour.© 2023 Poot et al.

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