• Shuang Liang, Weijuan Ma, Sihui Jia, Gang Zhao, Ying Li, Yaxin Li, Licun Wang, Zheng Liu, Jiao Liu, Hairui Gao, and Haiyan Wang.
• Department of Blood Transfusion, the Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.
• Medicine (Baltimore). 2023 Nov 17; 102 (46): e35996e35996.

RationalePerianal abscess is a common disease of the anus and intestine. Surgery is an important treatment option for perianal abscess. However, some patients have a long healing time, poor healing effect after surgery, or even pseudo-healing. Platelet-rich plasma (PRP) is rich in platelets that can release a large number of factors when activated and promote wound healing. Moreover, there are few reports on the use of PRP for wounds that are difficult to heal after perianal abscess surgery.Patient ConcernsThe patient had reported a complaint of perianal swelling and discomfort associated with anal pain, which was considered a perianal abscess. Ceftriaxone, fumigation, and sitz bath were administered after mixed hemorrhoid and perianal abscess surgeries were performed; however, the wound remained unhealed for more than 3 months, and there was a fistula under the skin.DiagnosisPerianal color ultrasonography revealed perianal abscess.InterventionsAutologous PRP treatment was performed 5 times for each patient.OutcomesThe postoperative wound healed within 15 days after 5 times PRP treatments.LessonsPRP is a novel treatment option for pseudo-healing.Copyright © 2023 the Author(s). Published by Wolters Kluwer Health, Inc.

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