• Shiting Zhang, Xuelu Jiang, and Peiyu Mao.
• The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China.
• Medicine (Baltimore). 2023 Nov 24; 102 (47): e36229e36229.

RationaleEndometriosis, a benign disease, has a malignant biological behavior and is highly prone to recurrence. Although gastrointestinal involvement is the most common site for extra-genital endometriosis, deep infiltrative endometriosis, which affects the mucosal layer, is very rare.Patient ConcernsA 44-year-old woman with a 6-month history of recurring abdominal pain and Hematochezia. The patient visited several hospitals over the past six months and was suspected to have been diagnosed with a digestive disease, for which medication was ineffective, leading to a great deal of anxiety.DiagnosesColonic endometriosis.InterventionsAfter a thorough imaging evaluation and preoperative discussion, laparoscopic colonic endometriosis resection under indocyanine green indication was performed by gynecologists and gastroenterologists.OutcomesAfter laparoscopic treatment, the patient's symptoms improved significantly, with occasional pain felt and no blood in the stool.LessonsThis case provides a rare example of sigmoid endometriosis causing periodic abdominal pain and Hematochezia. We report a clinical case to investigate the feasibility of an indocyanine green fluorescent contrast technique to guide the scope of surgery in laparoscopic deep infiltrative endometriosis surgery. In intestinal endometriosis surgery, indocyanine green fluoroscopy may indicate the lesion's precise localization.Copyright © 2023 the Author(s). Published by Wolters Kluwer Health, Inc.

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