• Mei Zhang, Ming He, and Ting Tang.
• Guizhou University of Traditional Chinese Medicine, Guiyang, China.
• Medicine (Baltimore). 2023 Nov 24; 102 (47): e36150e36150.

RationaleAtopic dermatitis (AD) is a burdensome skin disorder, especially in children. The prevalence of children with AD is increasing year by year in China. Typical symptoms like eczema-like lesions and severe pruritus can seriously affect the sleep quality and the growth and development of pediatric patients.Patient ConcernsWe observed a pair of fraternal twins, in which the younger sister had AD, while the elder one had no relevant medical history. At present, the height of the 2 individuals is significantly inconsistent, with a difference of about 10 cm.DiagnosesBased on the little patient's medical history and clinical manifestations, the diagnosis of AD was made.InterventionsThis little patient was treated with oral routine antihistamines, topical glucocorticoids and Dupilumab.OutcomesAt present, her rash and xerosis have significant improvement. She also have relief of generalized itching and improved sleep quality.LessonsPrevious studies have indeed shown that AD has a negative impact on children's height. This case leads us to consider the association between AD and height. It also gave us the opportunity to observe subsequent height changes after the intervention was carried out.Copyright © 2023 the Author(s). Published by Wolters Kluwer Health, Inc.

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