• J Coll Physicians Surg Pak · Dec 2023

    Acute Oral Mucositis During Hypo-Fractionated Radiation in Squamous Cell Carcinoma of Oral Cavity.

    • Agha Muhammad Hammad, Sehrish Abrar, Rabia Tahseen, Bilal Mazhar Qureshi, Asim Hafiz, and Ahmed Nadeem Abbasi.
    • Department of Oncology, The Aga Khan University Hospital, Karachi, Pakistan.
    • J Coll Physicians Surg Pak. 2023 Dec 1; 33 (12): 146014621460-1462.

    AbstractOral mucositis remains a concern in the treatment of head and neck malignancies. This small study included 11 patients treated by hypo-fractionated radiotherapy and assessed for oral mucositis. All patients received a radiation dose of 55 Gy in 20 fractions (2.75 Gy/fraction). At the end of the first week of radiation, three patients had Grade I oral mucositis. During the last week of radiation, most of the patients developed Grade II and III mucositis, 7 (64%) and 4 (36%), respectively. At one month follow-up, 5 (46%) of them had Grade I, while 2 (18%) had developed Grade II mucositis. At three months, 2 (18%) had Grade I mucositis, and none of the patients showed Grade II/III oral mucositis. Grade II oral mucositis was the most common grade found mainly in the last week of radiation therapy. None had Grade IV oral mucositis. Key Words: Acute oral mucositis, Hypo-fractioned radiation, Oral carcinoma.

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