• Cleve Clin J Med · Jul 2015

    Review

    Ceftaroline fosamil: A super-cephalosporin?

    • Riane J Ghamrawi, Elizabeth Neuner, and Susan J Rehm.
    • Clinical Pharmacist Specialist, Adult Antimicrobial Stewardship Department of Pharmacy, University Hospitals Case Medical Center, Cleveland, OH, USA.
    • Cleve Clin J Med. 2015 Jul 1; 82 (7): 437444437-44.

    AbstractCeftaroline is a broad-spectrum cephalosporin used to treat infections caused by a variety of microorganisms, including methicillin-resistant Staphylococcus aureus (MRSA) and multidrug-resistant Streptococcus pneumoniae. However, it is not active against Pseudomonas aeruginosa, Bacteroides fragilis, and carbapenem-resistant Enterobacteriaceae. Its approved indications include community-acquired bacterial pneumonia and bacterial infections of skin and skin structures. It has also been used off-label to treat osteomyelitis, endocarditis, and meningitis caused by ceftaroline-susceptible organisms.Copyright © 2015 Cleveland Clinic.

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