• Mahendra Raj Shrestha, Ajaya Basnet, Rajendra Maharjan, Sagar Ghimire, Nisha Khatri, Arju Shrestha, Lochan Karki, and Saujanya Karmacharya.
• Department of Clinical Laboratory, Nepal Armed Police Force Hospital, Balambu, Kathmandu, Nepal.
• JNMA J Nepal Med Assoc. 2023 Dec 1; 61 (268): 931933931-933.

IntroductionIn invasive cervical specimens or precursors, high-risk human papillomavirus Deoxyribonucleic acid may be detected to identify females at risk of developing cervical cancer. This study aimed to find out the prevalence of human papillomavirus among women undergoing Papanicolaou smear tests in a tertiary care centre.MethodsA descriptive cross-sectional study was conducted among women undergoing the Papanicolaou smear test in the Department of Gynaecologic Oncology, Nepal Armed Police Force Hospital, between 1 June 2022 and 15 November 2022. Ethical approval was obtained from the Ethical Review Board. A convenience sampling method was used. The point estimate was calculated at a 95% Confidence Interval.ResultsAmong the 199 women, 6 (3.02%) (0.64-5.40, 95% Confidence Interval) had human papillomavirus infection. The mean age of the infected females was 31.17±5.57 years. Human papillomavirus DNA for 16 and 18 were detected in 4 (66.67%) and 2 (33.33%) females, respectively.ConclusionsThe prevalence of human papillomavirus in females was found to be lower than other studies done in similar settings.Keywordscytology; histology; human papillomavirus; Nepal; prevalence.

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