• Juri Kawasaki, Naoko Mato, Hiroyuki Fujii, Kumiko Miura, Takafumi Mashiko, Shinshu Katayama, Yoshitaka Yamanouchi, Miki Sato, Toshikazu Takasaki, Ayako Takigami, Shu Hisata, Shin Nunomiya, Koichi Hagiwara,... more and Makoto Maemondo. less
• Division of Pulmonary Medicine, Department of Medicine, Jichi Medical University, Japan.
• Intern. Med. 2024 Apr 15; 63 (8): 116711721167-1172.

AbstractA 45-year-old woman was hospitalized with severe coronavirus disease 2019 pneumonia. Following cytokine storm-induced multiorgan failure and lethal arrhythmia, the patient developed a sustained coma with flaccid quadriplegia. A cerebrospinal fluid examination excluded infectious and immunogenic encephalopathies, and diffusion-weighted magnetic resonance imaging demonstrated high-intensity areas in the white matter with a cortex-sparing distribution, suggesting delayed post-hypoxic leukoencephalopathy. As a result of intensive cardiopulmonary support for a month, the neurological function gradually recovered. Based on the reversible clinical course noted in this patient, accurate diagnosis and persistent medical approaches are important for the management of coronavirus disease 2019-related delayed post-hypoxic leukoencephalopathy.

18 keywords...

hide…