• J Coll Physicians Surg Pak · Feb 2024

    Randomized Controlled Trial

    Dexketoprofen versus Tenoxicam in Acute Severe Pain Due to Primary Dysmenorrhea.

    • Deniz Aka Satar, Salim Satar, Muge Gulen, Selen Acehan, Nefise Tanridan Okcu, and Gonca Koksaldi Sahin.
    • Assisted Reproduction Unit, Andrology Laboratory, Health Sciences University, Adana City Training and Research Hospital, Adana, Turkiye.
    • J Coll Physicians Surg Pak. 2024 Feb 1; 34 (2): 160165160-165.

    ObjectiveTo evaluate the analgaesic efficacy of tenoxicam and dexketoprofen in patients admitted to the Emergency Medicine (EM) Clinic with severe acute pain due to primary dysmenorrhea (PD).Study DesignRandomised-controlled trial. Place and Duration of the Study: Emergency Medicine Clinic, Health Sciences University, Adana City Training and Research Hospital, Adana, Turkiye, from January to December 2022.MethodologyPatients presenting with PD, were divided into two groups of 60 each, administered 50 mg dexketoprofen and 20 mg tenoxicam intravenously. Visual analogue scale (VAS) scores were recorded at the 15th, 30th, 60th, and 120th minutes. VAS scores and ΔVAS scores were compared with the effectiveness of drugs, the need for rescue drugs and its side-effects.ResultsIntravenous (IV) dexketoprofen was administered to 60 of the patients and IV tenoxicam was administered to another 60. At the time of admission, mean VAS scores of the patients were 8.8 ± 0.9 for the dexketoprofen group and 8.6 ± 0.8 for the tenoxicam group. The VAS scores of the dexketoprofen group were found to be statistically significantly lower after 30 minutes with lower need for rescue analgaesics. ΔVAS scores of the dexketoprofen group were statistically significantly higher from the 30th minute.ConclusionAccording to the VAS scoring, IV dexketoprofen was a more effective drug than IV tenoxicam in patients who were admitted to the EM clinic with severe pain due to PD.Key WordsDexketoprofen, Primary dysmenorrhea, VAS score.

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