• African health sciences · Sep 2023

    Randomized Controlled Trial

    Effects of 0.15% ropivacaine alone and combination with sufentanil on epidural labor analgesia and adverse reactions.

    • Huanhui Zhong, Yongdong Wang, Yiqun Wang, and Heng Li.
    • Department of Anesthesiology, Affiliated Nanhua Hospital, University of South China, Hengyang 421002, Hunan Province, China.
    • Afr Health Sci. 2023 Sep 1; 23 (3): 569575569-575.

    ObjectiveThe aim of this study was to compare the impacts of 0.15% ropivacaine alone and 0.15% ropivacaine combined with sufentanil on epidural labor analgesia.MethodsA total of 297 eligible primiparae were randomly divided into group A (n=149, 0.15% ropivacaine + sufentanil) and group B (n=148, 0.15% ropivacaine). Visual analogue scale (VAS) scores prior to analgesia and 20 min following epidural medication, the maximum VAS score during labor, dosage of analgesic drugs, modified Bromage score, satisfaction degree, labor duration, delivery mode, 1-min and 5-min Apgar scores of newborns, adverse reactions during analgesia, and fever during labor were recorded.ResultsGroup A and B had similar VAS scores 20 min following epidural medication and maximum score during labor (P>0.05), which significantly fell compared with those before labor analgesia (P<0.05). The occurrence rates of nausea and vomiting were of significant difference (P<0.05).Conclusion0.15% ropivacaine alone achieves a comparable epidural labor analgesia effect to that of 0.15% ropivacaine + 0.05 µg/mL sufentanil on primiparae.© 2023 Zhong H et al.

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