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African health sciences · Sep 2023
Neutralising antibodies against SARS-CoV-2 give important information on Covid-19 epidemic evolution in Rabat, Morocco, March 2020-February 2021.
- Nadia Touil, Charifa Drissi Touzani, El Mostafa Benaissa, Jalal Kasouati, Zineb Rhazzar, Hicham El Annaz, Nadia El Mrimar, Lamiae Neffah, Rachid Abi, Rida Tagajdid, Safae El Kochri, Mariette Ducatez, Youssouf Akhouad, Ahmed Reggad, Zouhour El Kassimi, Abdelhamid Zrara, Fatna Bssaibis, ElMostapha El Fahime, Idriss Lahlou Amine, Abdelkader Belmekki, Yashpal Singh Malik, Mostafa Elouennass, and Khalid Ennibi.
- Unité de Culture Cellulaire, Centre des Maldies Infectieuses et Tropicales, Hôpital Militaire d'Instruction Mohammed V de Rabat, Morocco.
- Afr Health Sci. 2023 Sep 1; 23 (3): 400405400-405.
BackgroundThe SARS-CoV-2 is an extremely contagious and acute viral disease mainly affecting humans.ObjectiveTo estimate seroprevalence of SARS-CoV-2 neutralizing antibodies (NAbs) for illegible armed force individuals living in Rabat, Morocco.MethodA convenience sample (N = 2662) was conducted from May 2020 to February 2021. We used the standard neutralization assay to quantify the NAbs titers. A serum was positive when the titer was 1:4. High positive NAbs titers were defined when ≥ 1:32.ResultsDemographic and socioeconomic status did not affect seroprevalence data. An overall seroprevalence of 24,9% was found. Sera from blood donors, young recruits and auto-immune population had lower NAbs titers. However, titers were above 1:16 in 9% of the population with high risk of SARS-CoV-2 exposure. Seropositivity increased over time with values reaching peaks after the epidemic waves (2.4% in May 2020; 16.2% in August 2020; 22.7% in December 2020 and 37% in February 2021).ConclusionAnd increase of NAbs was observed over time and correlated with the post-epidemic waves of COVID-19 in Morocco.© 2023 Touil N et al.
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