• Kasereka Muteke, Milton W Musaba, David Mukunya, Jolly Beyeza, Julius N Wandabwa, and Paul Kiondo.
• Department of Obstetrics and gynecology, College of Health Sciences, Makerere University, P.O BOX 7072, Kampala, Uganda.
• Afr Health Sci. 2023 Sep 1; 23 (3): 273627-36.

BackgroundThe resolution of hypertension, proteinuria and AKI postpartum among women with preeclampsia is not well documented in Uganda.ObjectiveTo determine the time to resolution of hypertension, proteinuria and AKI postpartum until 6 weeks among women with preeclampsia in Mulago Hospital, Uganda.MethodsBetween August 2017 and April 2018, we measured blood pressure, urine protein and serum creatinine on days 1,7,21 and 42 postpartum among 86 women with preeclampsia. The primary outcomes were time to the resolution of hypertension, proteinuria and AKI. We fitted accelerated failure models using Stata 17's stintreg. command with a log normal distribution and obtained time ratios of selected exposures on time to resolution of hypertension, proteinuria and AKI intervals.ResultsThe median time to resolution of hypertension, proteinuria and AKI was seven (7) days (Inter quartile range, IQR 1-21). The time to resolution of hypertension among primiparous women was 3.5 times that of multiparous women [TR 3.5, 95%CI 1.1, 11.3]. No differences were observed in resolution of hypertension, proteinuria and acute kidney injury.ConclusionThe time to resolution of hypertension, proteinuria and AKI was seven days. We recommend larger studies with longer follow-up beyond six-weeks postpartum to inform revision of our guidelines.© 2023 Muteke K et al.

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