• African health sciences · Sep 2023

    Prevalence and predictors of hepatitis C infection among antenatal attendees in a tertiary hospital in Southern Nigeria.

    • Ganiyu Oluwedolapo Shittu, Aniekan Monday Abasiattai, Aniefiok Jackson Umoiyoho, and Ifeanyi Abraham Onwuezobe.
    • Department of Obstetrics/Gynaecology, University of Uyo Teaching hospital, Uyo, Nigeria.
    • Afr Health Sci. 2023 Sep 1; 23 (3): 455445-54.

    BackgroundHepatitis C virus infection as it specifically relates to pregnancy has been a neglected condition, thus its recognition and treatment in pregnancy is relevant because of the risks of the long-term complications of the infection in the mother, potential effects of the infection on the pregnancy and risk of vertical transmission to the newborn.ObjectivesTo determine the proportion of pregnant women with serologic markers of hepatitis C infection, identify risk factors as well as factors that predict the occurrence of the infection in them.MethodologyOver a 3-week period, blood samples from 456 pregnant women were assessed for antibodies to hepatitis C virus, while a pre-tested questionnaire was used to obtain socio-demographic data and the presence of risk factors in the University of Uyo Teaching Hospital, Nigeria.ResultsThe prevalence of HCV infection in pregnancy was 4.6%. No known risk factors for HCV infection in pregnancy were identified. Only increasing gestational age was a predictor of HCV infection in pregnancy in the study.ConclusionThe prevalence of hepatitis virus infection among the study population was high. Second trimester and increasing gravidity were protective of the infection in pregnancy. There is therefore need for introduction of general routine screening of all pregnant women presenting for antenatal care.© 2023 Shittu GO et al.

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