• Patient Prefer Adher · Jan 2024

    Case Reports

    Real-Time Experience of Abrocitinib for the Treatment of Mucous Membrane Pemphigoid: A Case Report.

    • Yan Teng, Mingyang Ren, Xianhong Yang, Wei Lu, and Xiaohua Tao.
    • Center for Plastic & Reconstructive Surgery, Department of Dermatology, Zhejiang Provincial People's Hospital, Affiliated People's Hospital of Hangzhou Medical College, Hangzhou, 310014, People's Republic of China.
    • Patient Prefer Adher. 2024 Jan 1; 18: 503506503-506.

    BackgroundMucous membrane pemphigoid (MMP), a rare autoimmune vesiculous and erosive disorder, may affect multiple mucous membranes, with the oral cavity being the most commonly affected site. Its treatment depends on the site(s) of mucosal involvement and disease severity.Patients And MethodsA 62-year-old female patient with MMP that predominantly involved the oral cavity strongly rejected systemic corticosteroid or immunosuppressive agents and was successfully treated with abrocitinib, a highly selective JAK-1 inhibitor with a good safety profile.ResultsThe case demonstrated good efficacy and safety profile of abrocitinib for the treatment of MMP with predominant oral involvement.ConclusionAbrocitinib is a promising agent for the treatment of MMP with oral involvement.© 2024 Teng et al.

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